In colorectal cancer, early-stage surgery carries high success; in advanced disease, regional and particle therapies targeting liver metastases are among Japan's strengths.
For liver metastases, heavy ion and catheter-based regional therapies may be evaluated.
Surgery is planned with minimally invasive techniques at Japanese centers.
Personalized vaccine (AFTV) can be discussed as an adjunct protocol in suitable cases.
The number and location of metastases and prior treatments determine the options; no method promises the same outcome for every patient.